Contact:

Department of Biological Chemistry
Indian Association for the Cultivation of Science
Phone:+91 33 2473 4971 [Ext. 1506 (O), 1513 (L)]
Fax: +91 33 2473 2805
E-mail : bcrm [ AT ] iacs.res.in

Background:

Rupa Mukhopadhyay received her B.Sc. with Honours in Chemistry from Presidency College (Calcutta University) in 1994 and her M.Sc. in Chemistry from IIT Kanpur in 1996. She read for her Doctoral degree in Biophysical and Bioinorganic Chemistry under the supervision of Prof. H. Allen O. Hill, FRS, in the University of Oxford, United Kingdom, and obtained her D.Phil. (Ph.D.) degree in 2000. After a brief sojourn at IIT Guwahati and IIT Kanpur, she moved to the Interdisciplinary Nanoscience Centre (iNANO) in Denmark and worked with Prof. Flemming Besenbacher on various projects in Nanotechnology till 2005. She joined at IACS as a Visiting Faculty in 2006, became an Assistant Professor in 2007, and an Associate Professor in 2012 .

Current Publications:

	S. Mishra, S. Ghosh and R. Mukhopadhyay*, Ordered self-assembled Locked Nucleic Acid (LNA) structures on gold(111) surface with enhanced single base mismatch recognition capability, Langmuir, 28, 4325-4333 (2012)
	T. Banerjee, P. Dubey and R. Mukhopadhyay*, DNA compaction by mononuclear platinum cancer drug cisplatin and the trisplatinum anticancer agent BBR3464: Differences and Similarities, Biochimie 94, 494-502, (2012).
	T. Rakshit and R. Mukhopadhyay*, Tuning band gap of holoferritin by metal core reconstitution with Cu, Co and Mn, Langmuir 27, 9681-9686, (2011).
	S. Ghosh and R. Mukhopadhyay*, An Atomic Force Microscopy Investigation on Self-assembled Peptide Nucleic Acid Structures on Gold(111) Surface, Journal of Colloid and Interface Science 360, 52-60, (2011).
	T. Rakshit, S. Banerjee and R. Mukhopadhyay*, Near-metallic Behavior of Warm Holoferritin Molecules on Gold(111) Surface, Langmuir 26(20), 16005-16012, (2010).

The present thrust of our research is Nanobiology/Bio-Nanotechnology. We are particularly interested in Nanomedicine where we primarily focus on understanding the effects of platinum cancer drugs on DNA topology at single molecule level; Nanoscale protein-based bioelectronics where we assess the utility of the iron storage protein Ferritin (human liver) as a potential molecular bioelectronic component; Nanoscale nucleic acid sensors where we develop bioactive films of alternative nucleic acids with an aim of achieving better DNA detection abilities; and Single Molecule level Structural Biology for probing the architecture of protein supramolecular assemblies of relevance in DNA Transcription using scanning probe microscopy approach.

Current Research

Group Members

Complete Publication

Selected Publication

IACS Home